Minted: - / 5000

1062 Edogestrone
155212eed94878f2ac87230a898c28a094dc70b33021122505f9bea4f6189ffb

Properties

Background

Blue
Bottle

Light blue
Cap

Light blue
Syringe

Yellow
Bubbles
No
Drops
No
Label
-

Chemistry

Formula
C26H38O5
Carbon
26
Polarity
Neutral

Edogestrone (, ) (developmental code name PH-218), or edogesterone, also known as 17α-acetoxy-3,3-ethylenedioxy-6-methylpregn-5-en-20-one, is a steroidal progestin and antiandrogen of the 17α-hydroxyprogesterone group which was synthesized in 1964 but was never marketed. Similarly to the structurally related steroid cyproterone acetate, edogestrone binds directly to the androgen receptor and antagonizes it, displacing androgens like testosterone from the receptor, though not as potently as cyproterone acetate. The drug has also been found to suppress androgen production, likely via progesterone receptor activation-mediated antigonadotropic activity.

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