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110 Basmisanil
1f1616b9592a653a0c3cd808c97bb60adb9172388854aea57c6dbb61f83f0543

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Properties

Chemistry

Basmisanil (; developmental codes RG-1662 and RO5186582) is a highly selective inverse agonist/negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome. As of June 2016, it is no longer studied. It is studied with schizophrenia patients.

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