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1124 Levoketoconazole
b47ee5ca049a6687eed7d709b274db783ffe78ebc1af0826449899ef4933ee4b

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Properties

Chemistry

Levoketoconazole (, ) (developmental code name COR-003; tentative brand name Recorlev, previously NormoCort), also known as (2S,4R)-ketoconazole, is a steroidogenesis inhibitor that is under development by Strongbridge Biopharma (formerly Cortendo AB) for the treatment of Cushing's syndrome. It is currently in phase III clinical trials for this indication. The drug is the levorotatory or (2S,4R) enantiomer of ketoconazole. It is expected to have greater potency, efficacy, and safety, including a lower risk of hepatotoxicity, relative to racemic ketoconazole.

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