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1255 Purmorphamine
2573a41514384596a900556da7f2a02d2bf475b2de0bba2cabd4cc06c3ab6688

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Properties

Chemistry

Purmorphamine was the first small-molecule agonist developed for the protein Smoothened, a key part of the hedgehog signaling pathway, which is involved in bone growth, cardiovascular regeneration and brain development as well as having a number of other functions in the body. Purmorphamine has been shown to induce osteogenesis in bone tissue as well as influencing growth and differentiation of neurons in the brain.

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