Minted: - / 5000

1351 Cyanoketone
7ca9291b554e07fa52f3e4073b7e2f9e891421051dda8a329515ab3069266087

Properties

Background

Red
Bottle

Red
Cap

Blue
Syringe

Red
Bubbles
No
Drops
No
Label
-

Chemistry

Formula
C23H33NO2
Carbon
23
Polarity
Neutral

Cyanoketone, also known as 2α-cyano-4,4',17α-trimethylandrost-5-en-17β-ol-3-one (CTM), is a synthetic androstane steroid and a steroidogenesis inhibitor which is used in scientific research. On account of its structural similarity to pregnenolone, cyanoketone binds to and acts as a potent, selective, and irreversible inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD), an enzyme that is responsible for the conversion of pregnenolone into progesterone, 17α-hydroxypregnenolone into 17α-hydroxyprogesterone, into androstenedione, and androstenediol into testosterone. As such, cyanoketone inhibits the production of both gonadal and adrenal steroids, including progesterone, androgens, estrogens, and corticosteroids. The drug is too toxic for therapeutic use in humans, and so has been used instead exclusively as a research tool.

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