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1361 Basimglurant
40d1c398bbd081d74cc46714ae320f2ba32d8e8d5c33a5a7f58089cd1775b744

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Properties

Chemistry

Basimglurant (INN) (developmental code names RG-7090, RO-4917523) is a negative allosteric modulator of the mGlu5 receptor which is under development by Roche and Chugai Pharmaceutical for the treatment of treatment-resistant depression (as an adjunct) and fragile X syndrome. As of November 2016, it has undergone phase II clinical trials for both of these indications.

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