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141 Hydroxynorketamine
605682467f8d55c2d618d01b7b77088faeaa6170537e0455ce900d14fb5c534e

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Properties

Chemistry

Hydroxynorketamine (HNK), or 6-hydroxynorketamine, is a minor metabolite of the anesthetic, dissociative, and antidepressant drug ketamine. It is formed by hydroxylation of the intermediate norketamine, another metabolite of ketamine. As of late 2019, (2R,6R)-HNK is in clinical trials for the treatment of depression.

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