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1612 Gevotroline
99491cc93c4c40c0b3ece51cc1634a10a892bbb53a44a922036aa501cf7feec4

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Properties

Chemistry

Gevotroline (WY-47,384) is an atypical antipsychotic with a tricyclic structure which was under development for the treatment of schizophrenia by Wyeth-Ayerst. It acts as a balanced, modest affinity D2 and 5-HT2 receptor antagonist and also possesses high affinity for the sigma receptor. It was well tolerated and showed efficacy in phase II clinical trials but was never marketed.

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