Miraculous Medicines

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1624 Inotersen
0c054c0a91d295ae71e65abf33383e4d61290c114e3ab5dd61eb2ebc83d1ecc6

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Inotersen, sold under the brand name Tegsedi, is a 2-MOE antisense oligonucleotide medication used for the treatment of nerve damage in adults with hereditary transthyretin-mediated amyloidosis. The sequence is TCTTG GTTACATGAA ATCCC, where C is methylated C, and the first and third section (bases 1-5 and 16-20, separated from the middle section by spaces) are MOE-modified.

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