Minted: - / 5000

1727 Fengabine
e29f3006f3479253332c5ef03c82ed9997d35a5a7132c9564279d12280d759db

Properties

Background

Yellow
Bottle

Pink
Cap

Orange
Syringe

Light green
Bubbles
No
Drops
No
Label
Leaf

Chemistry

Formula
C17H17Cl2NO
Carbon
17
Polarity
Neutral

Fengabine (SL-79,229) is a drug which was investigated as an antidepressant but was never marketed. Its mechanism of action is unknown, but its antidepressant effects are reversed by GABA_A receptor antagonists like bicuculline and it has hence been labeled as GABAergic; however, it does not actually bind to GABA receptors, nor does it inhibit GABA-T. In clinical trials, fengabine's efficacy was comparable to that of the tricyclic antidepressants, but with a more rapid onset of action and much less side effects. Notably, fengabine lacks any sedative effects.

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