Miraculous Medicines

teleport me to a random drug
Minted: - / 5000

1798 Cymserine
e26c0ea7b46ea820b116bfbc47b1e292088fd4a92b9d7ffe3659c3b9fac3f5bf

This DRUG has not been minted yet.
Mint it now with MetaMask!

Send:
ETH
and donate to medical research.
Note: transaction fees shown in metamask are an approximation and are likely to be smaller.

Properties

Chemistry

Cymserine is a drug related to physostigmine, which acts as a reversible cholinesterase inhibitor, with moderate selectivity (15×) for the plasma cholinesterase enzyme butyrylcholinesterase, and relatively weaker inhibition of the better-known acetylcholinesterase enzyme. This gives it a much more specific profile of effects that may be useful for treating Alzheimer's disease without producing side effects such as tremors, lacrimation, and salivation that are seen with the older nonselective cholinesterase inhibitors currently used for this application, such as donepezil. A number of cymserine derivatives have been developed with much greater selectivity for butyrylcholinesterase, and both cymserine and several of its analogues have been tested in animals, and found to increase brain acetylcholine levels and produce nootropic effects, as well as reducing levels of amyloid precursor protein and amyloid beta, which are commonly used biomarkers for the development of Alzheimer's disease (potentially indicating the drugs as candidates to be the first medicine capable of stopping, and even reversing, the progression of the disease).

From Wikipedia, the free encyclopedia. License: CC BY-SA.
≪ Previous
1797 Next ≫
1799
Made with on Earth by F. Boffa and T. Calemme
This website does not track you.
Read the contract on Etherscan