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205 Daridorexant
ff4c8a22223218fd2252475bd1f493decd7b7f291e20dc17a26356814ac30027

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Properties

Chemistry

Daridorexant (developmental code name ACT-541468), formerly known as nemorexant, is a dual orexin receptor antagonist (DORA) which was originated by Actelion Pharmaceuticals and is under development by Idorsia Pharmaceuticals for the treatment of insomnia. It acts as a selective dual antagonist of the orexin receptors OX1 and OX2. The medication has a relatively short elimination half-life of 6 to 10 hours. As of April 2020, daridorexant has passed its first phase III clinical trial for the treatment of insomnia.

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