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2172 Epiestriol
b396b91d172efe530485f0f179724aaeaf6cc05cb93af660436f9fcf88334b52

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Properties

Chemistry

Epiestriol (brand names Actriol, Arcagynil, Klimadoral), or epioestriol , also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is a minor and weak endogenous estrogen, and the 16β-epimer of estriol (which is 16α-hydroxy-17β-estradiol). Epiestriol is (or has previously been) used clinically in the treatment of acne. In addition to its estrogenic actions, epiestriol has been found to possess significant anti-inflammatory properties without glycogenic activity or immunosuppressive effects, an interesting finding that is in contrast to conventional anti-inflammatory steroids like hydrocortisone (a glucocorticoid).

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