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2336 Phthalylsulfathiazole
26c07c2e57b682559261fb2c796c9f135e15086e59d258450dd52e8c5b56d4a7

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Properties

Chemistry

Phthalylsulfathiazole (also known as sulfathalidine) belongs to the group of drugs called sulfonamides. The drug is a broad-spectrum antimicrobial that can treat different types of infections including intestinal. The mechanism of action depends on competitive antagonism with para-aminobenzoic acid and inhibition of dihydropteroate synthetase activity, which in turn leads to impaired synthesis of dihydrofolic acid and as a result its active metabolite necessary for the synthesis of purine and pyrimidine.

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