Minted: - / 5000

2528 Robalzotan
203c0a7d0ea844561efa808a1bd7dc7abe7909e94a0ef865a4f1a96acbc30690

Properties

Background

Orange
Bottle

Green
Cap

Light blue
Syringe

Gray
Bubbles
Yes
Drops
No
Label
-

Chemistry

Formula
C18H23FN2O2
Carbon
18
Polarity
Neutral

Robalzotan (NAD-299, AZD-7371) is a selective antagonist at the 5-HT_1A receptor. It was shown to completely reverse the autoreceptor-mediated inhibition of serotonin release induced by the administration of selective serotonin reuptake inhibitors like citalopram in rodent studies. It was subsequently investigated by AstraZeneca as a potential antidepressant but like many other 5-HT_1A ligands was discontinued. Later on it was researched for other indications such as irritable bowel syndrome but was dropped once again.

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