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2614 Triparanol
4ea3b7f1713841da94632c937461f31dfbf771dae226822924ef3f2e1511fe5d

Properties

Background

Brown
Bottle

Purple
Cap

Light blue
Syringe

Purple
Bubbles
Yes
Drops
Yes
Label
Bacterium

Chemistry

Formula
C27H32ClNO2
Carbon
27
Polarity
Neutral

Triparanol (, ; brand name and development code MER/29, as well as many other brand names) was the first synthetic cholesterol-lowering drug. It was patented in 1959 and introduced in the United States in 1960. It was withdrawn in 1962 due to severe adverse effects such as nausea and vomiting, vision loss due to irreversible cataracts, alopecia, skin disorders (e.g., dryness, itching, peeling, and "fish-scale" texture), and accelerated atherosclerosis and is now considered to be obsolete.

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