Miraculous Medicines

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2629 Dotarizine
08c4bc4e30847f5b4c1ad27e6a6772abd72f09c580b5c943246a1af76a3413a9

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Properties

Chemistry

Dotarizine is a drug used in the treatment of migraine, which acts as a calcium channel blocker, and also as an antagonist at the 5HT2A receptor, and to a lesser extent at the 5HT1A and 5HT2C receptors. The anti-migraine action is thought to be due to its action as a vasodilator, but it also has some anxiolytic effects and blocks amnesia produced by electroconvulsive shock in animals.

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