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2744 Pyrithyldione
16424dce3b24856ed881efeedd43e06553ee5f32818f2794807467ac046b9c61

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Properties

Chemistry

Pyrithyldione (Presidon, Persedon) is a psychoactive drug invented in 1949. An improved method of manufacture was patented by Roche in 1959. It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates. Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect. Pyrithyldione is also a CYP2D6 inducer but is not as potent as glutethimide In studies, it increased the O-Demethylation of codeine by 20%.

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