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3003 Vorozole
1ba5c48377aefa7a70b3d3e8eaaf004473e8b6dfcbe7cf1b12f3c1cd81265ebe

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Properties

Chemistry

Vorozole (developmental code name R-76713; former tentative brand name Rizivor) is an imidazole based competitive inhibitor of the aromatase enzyme. It underwent clinical testing for evaluation for use as an antineoplastic agent; however it was withdrawn from testing when no difference was detected in the duration of median survival as compared to the progestational agent megestrol acetate and research instead focused on the other third generation aromatase inhibitors anastrozole, letrozole and exemestane.

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