Minted: - / 5000

3015 Elzasonan
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Properties

Background

Red
Bottle

Light blue
Cap

Orange
Syringe

Green
Bubbles
No
Drops
No
Label
Cross

Chemistry

Formula
C23H23N3O5
Carbon
23
Polarity
Neutral

Elzasonan (CP-448,187) is a selective 5-HT_1B and 5-HT_1D receptor antagonist that was under development by Pfizer for the treatment of depression but was discontinued, possibly due to poor efficacy. By preferentially blocking 5-HT_1B and 5-HT_1D autoreceptors, elzasonan is thought to enhance serotonergic innervations originating from the raphe nucleus, thereby improving signaling to limbic regions like the hippocampus and prefrontal cortex and ultimately resulting in antidepressant effects.

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