Minted: - / 5000

3032 Cisapride
e7a92cefd06160e398b1ecc2459ec3e47e89dda70c23919b6dabd70b8e4aca27

Properties

Background

Yellow
Bottle

Light green
Cap

Red
Syringe

Light blue
Bubbles
No
Drops
No
Label
-

Chemistry

Formula
C23H29ClFN3O4
Carbon
23
Polarity
Neutral

Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT₄ receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. It has been sold under the trade names Prepulsid (Janssen-Ortho) and Propulsid (in the United States). It was discovered by Janssen Pharmaceuticals in 1980. In many countries, it has been either withdrawn from the market or had its indications limited due to incidences of serious cardiac side-effects.

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