Minted: - / 5000

3054 Etiocholanolone
db33e5adc0db3b779fab3a0fe70dfe302b8ab96f03f31a85df5fc5bef1d98f52

Properties

Background

Orange
Bottle

Purple
Cap

Light blue
Syringe

Purple
Bubbles
No
Drops
No
Label
-

Chemistry

Formula
C19H30O2
Carbon
19
Polarity
Neutral

Etiocholanolone, also known as 5β-androsterone, as well as 3α-hydroxy-5β-androstan-17-one or etiocholan-3α-ol-17-one, is an etiocholane (5β-androstane) steroid as well as an endogenous 17-ketosteroid that is produced from the metabolism of testosterone. It causes fever, immunostimulation, and leukocytosis, and is used to evaluate adrenal cortex function, bone marrow performance, and in neoplastic disease to stimulate the immune system. Etiocholanolone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABA_A receptor, and possesses anticonvulsant effects. The unnatural enantiomer of etiocholanolone is more potent as a positive allosteric modulator of GABA_A receptors and as an anticonvulsant than the natural form.

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