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3164 Pacritinib
8437d253be2d1c749d155e7a48f6d067b86d40cbd3394d20f2ce5fea5b393015

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Properties

Chemistry

Pacritinib (INN) is a macrocyclic Janus kinase inhibitor that is being developed for the treatment of myelofibrosis. It mainly inhibits Janus kinase 2 (JAK2) and Fms-like tyrosine kinase 3 (FLT3). The drug was in Phase III clinical trials .

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