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3197 Irazepine
1b78e6966d948501ca9b5a3319a5dd4747b4803f66a50fb5a8ec52ce0f2d8106

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Properties

Chemistry

Irazepine (Ro 7-1986/1) is a benzodiazepine derivative containing isothiocyanate functional group. It is a non-competitive benzodiazepine binding site antagonist. Irazepine and other alkylating benzodiazepine, kenazepine, bind to brain benzodiazepine receptors in a non-competitive (covalent) fashion in vitro, and may exert a long-lasting anticonvulsant effect.

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