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3525 Almorexant
858d70517c737933508c9e50b43aad8817931bd428a1dad6f1fab62ef24a0203

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Properties

Chemistry

Almorexant (INN; development code ACT-078573) is an orexin antagonist, functioning as a competitive receptor antagonist of the OX1 and OX2 orexin receptors, which was being developed by the pharmaceutical companies Actelion and GSK for the treatment of insomnia. Development of the drug was abandoned in January 2011 due to undisclosed issues pertaining to almorexant's safety profile.

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