Miraculous Medicines

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3528 Asimadoline
d96d39fd8408821e2959dd18a8b819620143f224cd459e759ceb1b2920c1b540

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Properties

Chemistry

Asimadoline (EMD-61753) is an experimental drug which acts as a peripherally selective κ-opioid receptor (KOR) agonist. Because of its low penetration across the blood–brain barrier, asimadoline lacks the psychotomimetic effects of centrally acting KOR agonists, and consequently was thought to have potential for medical use. It has been studied as a possible treatment for irritable bowel syndrome, with reasonable efficacy seen in clinical trials, but it has never been approved or marketed.

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