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3690 Epostane
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Properties

Background

Red
Bottle

Green
Cap

Light green
Syringe

Green
Bubbles
No
Drops
No
Label
Bacterium

Chemistry

Formula
C22H31NO3
Carbon
22
Polarity
Neutral

Epostane (INN, USAN, BAN) (developmental code name WIN-32729) is an inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD) that was developed as a contraceptive, abortifacient, and oxytocic drug but was never marketed. By inhibiting 3β-HSD, epostane blocks the biosynthesis of progesterone from pregnenolone (and also the conversion of dehydroepiandrosterone to androstenedione), thereby functioning as an antiprogestogen and terminating pregnancy. The drug was trialed and in a study was found to be slightly more effective at inducing abortion relative to mifepristone.

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