Minted: - / 5000

3779 Esmirtazapine
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Properties

Background

Blue
Bottle

Light green
Cap

Light blue
Syringe

Light green
Bubbles
No
Drops
No
Label
-

Chemistry

Formula
C17H19N3
Carbon
17
Polarity
Neutral

Esmirtazapine (ORG-50,081) is a drug which was under development by Organon for the treatment of insomnia and vasomotor symptoms (e.g., hot flashes) associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology, including inverse agonist actions at H₁ and 5-HT₂ receptors and antagonist actions at α₂-adrenergic receptors. As of March 2010, Merck terminated internal clinical development program for esmirtazapine, for hot flashes and insomnia, for strategic reasons.

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