Miraculous Medicines

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3806 Altinicline
9e83fb32dbc5c626095bdadff7a480d4928fd318054151a9ec7fab16c3e2a86a

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Properties

Chemistry

Altinicline (SIB-1508Y, SIB-1765F) is a drug which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It stimulates release of dopamine and acetylcholine in the brain in both rodent and primate models, and progressed as far as Phase II clinical trials for Parkinson's disease, where "no antiparkinsonian or cognitive-enhancing effects were demonstrated", although its current status is unclear.

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