Miraculous Medicines

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384 Ibodutant
149dcf386d240a6d0636ae8fa96d2d8d48f5c159d4c10a30465ffbda6bf93a37

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Properties

Chemistry

Ibodutant was a candidate drug for irritable bowel syndrome diarrhea, developed by The Menarini Group. , it underwent a multicentre double blind efficacy clinical study. Ibodutant selectively blocks the tachykinin receptor NK2, with blockade practically complete in nanomolar concentrations. A phase 2 trial in Europe (the IRIS-2 trial) completed in May 2012 with positive results. A 52-week phase 3 study was terminated as of 2015 because of low response and negative results of study NAK-06.

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