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388 Samidorphan
9a2b8c6632e08195af51dbb053908fad462554a238b60fdbed92d1aba66e385a

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Properties

Chemistry

Samidorphan (INN, USAN) (developmental code names ALKS-33, RDC-0313), also known as 3-carboxamido-4-hydroxynaltrexone, is an opioid antagonist that preferentially acts as an antagonist of the μ-opioid receptor (MOR). It is under development by Alkermes for the treatment of major depressive disorder and possibly other psychiatric conditions.

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