Miraculous Medicines

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3929 Rolapitant
cba7fc07c3b78d49ce0b2ff6476d523e01902ae8443c74f1caaef55ca7f34255

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Properties

Chemistry

Rolapitant (INN, trade name Varubi in the US and Varuby in the European Union) is a drug originally developed by Schering-Plough and licensed for clinical development by Tesaro, which acts as a selective NK1 receptor antagonist (antagonist for the NK1 receptor). It has been approved as a medication for the treatment of chemotherapy-induced nausea and vomiting (CINV) after clinical trials showed it to have similar or improved efficacy and some improvement in safety over existing drugs for this application.

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