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3951 Dihydrexidine
a0a2a19c587513bfda6afe88878a43e10429ac73b0a28ab43ae7e7c841e3d7c1

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Dihydrexidine (DAR-0100) is a moderately selective full agonist at the dopamine D1 and D5 receptors. It has approximately 10-fold selectivity for D1 and D5 over the D2 receptor. Although dihydrexidine has some affinity for the D2 receptor, it has functionally selective (highly biased) D2 signaling, thereby explaining why it lacks D2 agonist behavioral qualities.

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