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4103 Ecallantide
5c0c70ffe68ba0d65371ffc2d92e6692190d1bf4223eecabce46f7837e2f0a39

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Properties

Chemistry

Ecallantide (trade name Kalbitor) is a drug used for the treatment of hereditary angioedema (HAE) and in the prevention of blood loss in cardiothoracic surgery. It is an inhibitor of the protein kallikrein and a 60-amino acid polypeptide which was developed from a Kunitz domain through phage display to mimic antibodies inhibiting kallikrein.

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