Miraculous Medicines

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4121 Tafamidis
9bae6fffa233361571b7bb13b9b7c04fb63ba3dd0b06a3392d2f6b6597323b2e

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Properties

Chemistry

Tafamidis, sold under the brand names Vyndaqel and Vyndamax, is a medication used to delay disease progression in adults with certain forms of transthyretin amyloidosis (ATTR). It can be used to treat both hereditary forms (hATTR), familial amyloid cardiomyopathy (FAC) and familial amyloid polyneuropathy (FAP), as well as wild-type transthyretin amyloidosis (wtATTR, formerly called senile systemic amyloidosis). It works by stabilizing the quaternary structure of the protein transthyretin. In people with ATTR, transthyretin falls apart and forms clumps (amyloids) that harm tissues including nerves and the heart.

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