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4131 Lortalamine
b38b77796e458b2c7bb21cced3ce91c83f50fe227d3ca5d40b69728a595a56bd

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Properties

Chemistry

Lortalamine (LM-1404) is an antidepressant which was synthesized in the early 1980s. It acts as a potent and highly selective norepinephrine reuptake inhibitor. Lortalamine was under development for clinical use but was shelved, likely due to the finding that it produced ocular toxicity in animals. It has been used to label the norepinephrine transporter in positron emission tomography studies.

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