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4150 Opigolix
4946220ab56e411572bb8c5a0743db1b454190ff6d8e2b333e423e911e0c294f

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Properties

Chemistry

Opigolix (, ; developmental code name ASP-1707) is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which was under development by Astellas Pharma for the treatment of endometriosis and rheumatoid arthritis. It was also under investigation for the treatment of prostate cancer. It reached phase II clinical trials for both endometriosis and rheumatoid arthritis prior to the discontinuation of its development in April 2018.

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