Minted: - / 5000

4651 Cyclotriol
a38c24940b0b6714f1a11470771ec9ea6638dd7e77d933d4abc8c6b6ddd63fd0

Properties

Background

Gray
Bottle

Light blue
Cap

Gray
Syringe

Purple
Bubbles
Yes
Drops
No
Label
Cross

Chemistry

Formula
C20H26O3
Carbon
20
Polarity
Neutral

Cyclotriol (developmental code name ZK-136295; also known as 14α,17α-ethanoestriol) is a synthetic estrogen which was studied in the 1990s and was never marketed. It is a derivative of estriol with a bridge between the C14α and C17α positions. The drug has 40% of the relative binding affinity of estradiol for the human ERα. It showed an absolute bioavailability of 40% with high interindividual variability and an elimination half-life of 12.3 hours in pharmacokinetic studies in women.

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