Miraculous Medicines

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601 Telapristone
7d92b07ac7afdb90b7b0ae1cd8a44b01de5b61bc1645ba0970d7e70963ca363a

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Properties

Chemistry

Telapristone , as telapristone acetate (proposed brand names Proellex, Progenta; former code name CDB-4124), is a synthetic, steroidal selective progesterone receptor modulator (SPRM) related to mifepristone which is under development by Repros Therapeutics for the treatment of breast cancer, endometriosis, and uterine fibroids. It was originally developed by the National Institutes of Health (NIH), and, as of 2017, is in phase II clinical trials for the aforementioned indications. In addition to its activity as an SPRM, the drug also has some antiglucocorticoid activity.

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