Minted: - / 5000

638 Alaproclate
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Properties

Background

Red
Bottle

Light blue
Cap

Orange
Syringe

Yellow
Bubbles
No
Drops
No
Label
Cross

Chemistry

Formula
C13H18ClNO2
Carbon
13
Polarity
Neutral

Alaproclate (developmental code name GEA-654) is a drug that was being developed as an antidepressant by the Swedish pharmaceutical company Astra AB (now AstraZeneca) in the 1970s. It acts as a selective serotonin reuptake inhibitor (SSRI), and along with zimelidine and indalpine, was one of the first of its kind. Development was discontinued due to the observation of liver complications in rodent studies. In addition to its SSRI properties, alaproclate has been found to act as a non-competitive NMDA receptor antagonist, but does not have discriminative stimulus properties similar to phencyclidine.

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