Minted: - / 5000

700 Sparsomycin
7565096a2d0c3be289048023c9b4194263c790b47929a1c9acfdc49c323e1d59

Properties

Background

Brown
Bottle

Light green
Cap

Purple
Syringe

Orange
Bubbles
No
Drops
Yes
Label
Heart

Chemistry

Formula
C13H19N3O5S2
Carbon
13
Polarity
Neutral

Sparsomycin is a compound, initially discovered as a metabolite of the bacterium Streptomyces sparsogenes, which binds to the 50S ribosomal subunit and inhibits protein synthesis through peptidyl transferase inhibition. As it binds to the 50S ribosomal subunit, it induces translocation on the 30S subunit. It is a nucleotide analogue. It was also formerly thought to be a possible anti-tumor agent, but interest in this drug was later discarded after it was discovered that it resulted in retinopathy and as a tool to study protein synthesis; it is not specific for bacterial ribosomes and so not usable as an antibiotic.

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