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798 Lesopitron
a4a316cef955ea4e44b8407da0b5f4f76d39bc6e7a79b6df0f31318394ee2e8b

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Properties

Chemistry

Lesopitron (E-4424) is a selective full agonist of the 5-HT1A receptor which is structurally related to the azapirones. In 2001 it was under development by Esteve as an anxiolytic for the treatment of generalized anxiety disorder (GAD). It made it to phase II clinical trials but was apparently discontinued as no new information on lesopitron has surfaced since.

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