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844 Binedaline
81ed7c2b05ad4ceb7fde3cbb2942723a6e99cbcd09698dc45f31bbe2f1ca1585

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Properties

Chemistry

Binedaline (also called binodaline or binedaline hydrochloride;) is a drug that was investigated as an antidepressant in the 1980s but was never marketed. It acts as a selective norepinephrine reuptake inhibitor (Ki = 25 nM), with relatively insignificant influence on the serotonin (Ki = 847 nM) and dopamine (Ki >= 2 μM) transporters. It has negligible affinity for the α-adrenergic, mACh, H1, or 5-HT2 receptors.

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