Minted: - / 5000

867 Azastene
ce5cd3d81b71049df39d351d89510738c5d47eda76fd53af04dad5b442d76bde

Properties

Background

Green
Bottle

Light green
Cap

Light blue
Syringe

Yellow
Bubbles
No
Drops
Yes
Label
-

Chemistry

Formula
C23H33NO2
Carbon
23
Polarity
Neutral

Azastene (INN, USAN) (developmental code name WIN-17625) is a steroidogenesis inhibitor described as a contraceptive, luteolytic, and abortifacient which was never marketed. It acts as a competitive inhibitor of 3β-hydroxysteroid dehydrogenase (IC₅₀ = 1 μM), and thereby inhibiting the formation of progesterone, corticosteroids, androgens, and estrogens. Due to inhibition of corticosteroid synthesis, azastene is immunosuppressive.

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