Minted: - / 5000

874 Chaetochromin
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Properties

Background

Brown
Bottle

Purple
Cap

Yellow
Syringe

Purple
Bubbles
No
Drops
No
Label
-

Chemistry

Formula
C30H26O10
Carbon
30
Polarity
Neutral

Chaetochromin, also known as 4548-G05, is an orally active, small-molecule, selective agonist of the insulin receptor. It has potent and long-lasting antidiabetic activity in vivo in mice. The drug may represent a novel potential therapeutic agent for the treatment of diabetes which is more convenient and tolerable to administer than injected insulin. It was discovered in 1981 in Chaetomium gracile fungi, and its interaction with the insulin receptor was identified in 2014.

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