Miraculous Medicines

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95 Sumanirole
ed1dbf5c1848f5798a28e2f0552e1a81d8321085847cf20094e3c06bfe66dd75

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Properties

Chemistry

Sumanirole (PNU-95,666) is a highly selective D2 receptor full agonist, the first of its kind to be discovered. It was developed for the treatment of Parkinson's disease and restless leg syndrome. While it has never been approved for medical use it is a highly valuable tool compound for basic research to identify neurobiological mechanisms that are based on a dopamine D2-linked (vs. D1-, D3-, D4-, and D5-linked) mechanism of action.

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