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960 Eutropoflavin
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Properties

Background

Yellow
Bottle

Orange
Cap

Light blue
Syringe

Blue
Bubbles
No
Drops
No
Label
Cross

Chemistry

Formula
C17H15NO4
Carbon
17
Polarity
Neutral

Eutropoflavin (4'-Dimethylamino-7,8-dihydroxyflavone) is a synthetic flavone and selective small-molecule agonist of TrkB, the main receptor of brain-derived neurotrophic factor (BDNF), which was derived from structural modification of tropoflavin (7,8-DHF). Relative to tropoflavin, eutropoflavin possesses higher agonistic activity at TrkB, is significantly more potent than tropoflavin both in vitro and in vivo, and has a longer duration of action (peaking at 4 hours and "partially decaying" at 8~16 hours in rodents). The compound has been found to produce neuroprotective, neurogenic, and antidepressant-like effects in animals.

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