Miraculous Medicines

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970 Tampramine
0be6d185acd62fef483c6b95dc0cb90e5bc20ae3209891a9f40a862f4d14a132

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Properties

Chemistry

Tampramine (AHR-9,377) is a tricyclic antidepressant (TCA) which was developed in the 1980s but was never marketed. Despite being a TCA, it acts as a selective norepinephrine reuptake inhibitor and has negligible affinity for adrenergic, histaminergic, and muscarinic receptors. It was found to be effective in the forced swim test (FST) model of depression in animal studies but is not known to have ever been trialed in humans.

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