Minted: - / 5000

1664 Tetrahydrodeoxycorticosterone
30b76bea92c02c301c1d882319823620b75067d28a27d7ad3aaebfa40602a9c2

Properties

Background

Yellow
Bottle

Orange
Cap

Blue
Syringe

Blue
Bubbles
No
Drops
No
Label
Bacterium

Chemistry

Formula
C21H34O3
Carbon
21
Polarity
Neutral

Tetrahydrodeoxycorticosterone (abbreviated as THDOC; 3α,21-dihydroxy-5α-pregnan-20-one), also referred to as allotetrahydrocorticosterone, is an endogenous neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone by the action of two enzymes, 5α-reductase type I and 3α-hydroxysteroid dehydrogenase. THDOC is a potent positive allosteric modulator of the GABA_A receptor, and has sedative, anxiolytic and anticonvulsant effects. Changes in the normal levels of this steroid particularly during pregnancy and menstruation may be involved in some types of epilepsy (catamenial epilepsy) and premenstrual syndrome, as well as stress, anxiety and depression.

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