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2763 Plicamycin
431fad6ad44165989c9b04e27d2a02bf3b85f99839b5eafe4aa4eaf0feb3e78c

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Properties

Chemistry

Plicamycin (INN, also known as mithramycin; trade name Mithracin) is an antineoplastic antibiotic produced by Streptomyces plicatus. It is an RNA synthesis inhibitor. The manufacturer discontinued production in 2000. Several different structures are currently reported in different places all with the same chromomycin core, but with different stereochemistry in the glycoside chain, a 1999 study has re-investigated the compound and proposed a revised structure.

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